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| Version | User | Scope of changes |
|---|---|---|
| Jan 6 2009, 4:29 PM EST | M.J.Fuller | 73 words added, 7 words deleted |
| Jan 5 2009, 8:16 PM EST | M.J.Fuller |
Soft Tissue Calcification identification can be a useful skill for radiographers who work in the Emergency Department. Timely identification of soft tissue calcification can expedite the patient's imaging and save the patient from unnecessary additional imaging (particularly comparison views). From the Radiologist's point of view soft tissues calcifications are usually not problematicproblematic, but occasionally pop up as incidental findings and, as one author noted, "it behooves the radiologist to say something intelligent about them" http://www.rad.washington.edu/academics/academic-sections/msk/teaching-materials/online-musculoskeletal-radiology-book/soft-tissue-calcifications
Type Incidence Examples Appearance Dystrophic Calcification 95 - 98 % small to large amorphous Ca++ in the damaged tissue -- may progress to ossification (formation of cortex and medullary space are then seen) Metastatic Calcification 1 - 2% Entities such as renal failure, hyperparathyroidism, sarcoidosis, milk-alkali syndrome, etc. can lead to metastatic calcifications. finely speckled calcification throughout soft tissues Calcinosis 1 - 2% Calcification of cutaneous, subcutaneous or deep connective tissue.
- Not associated with metabolic disturbance.
- May be associated with with collagen-vascular disease.
- 3 Types:
1. Calcinosis circumscripta
2. Calcinosis universalis
3. Tumoral calcinosisChondrocalcinosis
(CPPD)(Calcium pyrophosphate dihydrate deposition disease- CPPD)1 - 2 % CalciumNon-specific calcification of cartilage
Gout -- calcium urate crystals
Pseudogout - calcium pyrophosphate
Ochronosis dihydrate– depositionhomogentisic diseaseacid oxidase
Hyperparathyroidism
Diabetes
Degenerative disea
- (CPPD) is usually associated with chondrocalcinosis.
This typically appears as a fine white line overlying the hyaline articular cartilage.- CPPD is also associated with calcifications in the soft tissues of the spine.
Synovial Chondromatosis http://www.squidoo.com/bonexray
http://www.rad.washington.edu/academics/academic-sections/msk/teaching-materials/online-musculoskeletal-radiology-book/soft-tissue-calcifications
The Department of Radiology at the University of Washington provide a simple english description of dystrophic calcification as follows
| "As you can see, almost every calcification that one sees in the soft tissues in actual radiographic practice is due to dystrophic calcification. What does this mean? Simply this: when tissue is damaged, the body responds to this injury in a nonspecific manner by invoking the generic inflammatory response reaction. This sometimes ends with calcification of the damaged tissue. This calcification is probably usually only microscopic, but is occasionally enough to be seen radiographically." | http://www.rad.washington.edu/academics/academic-sections/msk/teaching-materials/online-musculoskeletal-radiology-book/soft-tissue-calcifications |
Differential diagnosis of dystrophic calcificationMnemonic = VINDICATE (VINDAT)
V = Venous - Phlebolith
I = Infection - Cysticercosis
N = Neoplasm - Osteosarcoma
D = Drugs - Vitamin D overdose
A = Autoimmune - Dermatomyositis
T = Trauma - Hematoma, Heterotopic ossification
Dystrophic calcification associated with hip joint (arrowed)